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TIL Jackie Chan turned down to play the main antagonist "Koji Sato" for the 1989 film Black Rain because he feared audiences would hate to see him play as the bad guy. Harrison Ford and Kurt Russell were highly considered for the main protagonist "Nick Conklin" before Michael Douglas was cast.

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M7NRB TIL About the Personalized Onco Genomics (POG) trials. Started in 2012, doctors have been using patients' DNA to find personalized treatments to fight cancer.
W70do TIL About Diana Budisavljević, the female Schindler, who undertook one of the greatest humanitarian acts in WWII, by saving over 7,700 children from concentration camps in the area of what is today's Croatia
WxVY TIL Walt Disney was fired from a newspaper company for lacking creativity.
neLwo TIL that the B/W dots that you see on TV, as well as the background "hiss" that you hear in-between radio channels are actually fragments of the Big Bang AKA "radiation leftover" or "cosmic microwave background radiation"
gdPb TIL The Simpsons Movie Is Banned In Burma Necause The Characters Are “Too Yellow”