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TIL that when bears hibernate, they "hold it in" for almost half a year. This is due to a fecal plug that forms in their lower intestine that prevents them from pooping while hibernating.

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b9KOa TIL that eating grapefruit (and a few of its close relatives) can increase the side effects of certain medications by disrupting a specialized group of proteins in your liver and small intestine called cytochrome P450 (CYPs).
jNdKj TIL in 1994, 17 year old Rashida Jones (aka Ann Perkins in Parks and Rec) wrote an open letter addressing 2Pac's scathing remarks about her parents' interracial marriage. After working things out, he became friends with Rashida and her family, and went on to date Rashida's sister prior to his death.
M7mXV TIL Pious III was elected Pope on 22 September 1503 and died only 26 days later. During his election, everyone was aware that he was seriously ill, but electing the neutral Pious helped the two rivaling factions in the conclave to buy just enough time to continue their negotiations and politicking
Z8oBD TIL the last guy to commit seppuku (ritual suicide) was Yukio Mishima in 1970. He was a japanese nationalist author, actor and director who had his own milita and tried to stage a oup d'état by taking over the armed forces heaquaters. He killed himself in the commandants office when it failed.
6EQ0m TIL In China, killing panda is punishable by death